All medicines have potential side effects. But the side effects associated with the Varicella Vaccine are generally mild. The most common are pain, redness, or swelling at the injection site. A small percentage of people develop a mild rash, usually around the spot where the shot was given. Severe side effects are very rare.
It is also possible for a person who has been vaccinated for chickenpox to develop chickenpox at some later point in life. When that happens, the disease is almost always milder and the recovery more rapid than for people who have not had the shots. The lesions also may not follow the same crusting pattern and the vesicles may not have as much fluid in them when a vaccinated patient develops the virus.
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